Health Condition 1: P019- Newborn affected by maternal complication of pregnancy, unspecified
Conditions
Interventions
Intervention1: Initiation of delivery room stabilization with 60% oxygen followed by subsequent titration to achieve pre-defined oxygen saturation targets: Preterm neonates of gestational age 34 weeks
Sponsors
All India Institute of Medical Sciences Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: Inborn preterm neonates with gestational age less than 34 weeks requiring respiratory support for delivery room stabilization as per American Heart Association Neonatal Resuscitation Program (AHA-NRP) 2020 guidelines.
Exclusion criteria
Exclusion criteria: 1. Neonates with birth weight 2. Non availability of oxygen blender at delivery area 3. Major congenital anomalies 4. Inability to obtain parental consent 5. Parental decision - not to resuscitate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of neonates achieving a target oxygen saturation of â?¥80%.Timepoint: At 5 minutes of life. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Time to achieve HR100/min 2. Time to achieve SpO2 85% 3. Heart rate and SpO2 at different time intervals 4. Cerebral regional oxygen saturation (crSO2) at 1 hour of life 5. Need for delivery room intubation 6. Need for surfactant use 7. Need and duration of respiratory support 8. Duration of supplemental oxygen therapy 9. Duration of hospital stay 10. Final outcome 11. Incidence of adverse events Timepoint: During hospital stay and at discharge | — |
Countries
India
Contacts
Public ContactSriparna Basu
All India Institute of Medical Sciences, Rishikesh
Outcome results
None listed