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During awake intubation under guidance of a handheld probe fitted with a camera, addition of dexmedetomidine to lignocaine can be a better alternative to lignocaine alone in anaesthetising upper airway.

In atomisation, addition of dexmedetomidine to lignocaine can be a better alternative than lignocaine alone in airway preparation for awake fibreoptic intubation - a randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/048942
Enrollment
70
Registered
2023-01-12
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T300- Burn of unspecified body region, unspecified degree Health Condition 2: S026- Fracture of mandible Health Condition 3: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 4: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: In atomisation use of dexmedetomidine as an additive to lignocaine for 2 mins in airway preparation for awake fibreoptic intubation Control Intervention1: Lignocaine: I

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I & II scheduled for elective reconstructive plastic surgery requiring awake fibreoptic intubation (AFOI) Patients giving consent for fibre optic intubation, Known or anticipated difficult airway

Exclusion criteria

Exclusion criteria: ASAGrade III IV V Emergency surgery Psychiatric illness Chronic illness Systemic disease Skin infection diabetes hypertension H/O allergy to drug Alcohol abuse smoker

Design outcomes

Primary

MeasureTime frame
Ease of intubation as judged by cough and gag scoreTimepoint: Time from fibreoptic scope insertion to confirmation of endotracheal intubation by capnography—

Secondary

MeasureTime frame
Cord visibility statusTimepoint: During the procedure;Hemodynamic parameter heart rate systolic blood pressure diastolic blood pressure mean arterial pressure O2 saturationTimepoint: 1 min 3 min 5 min 10 min interval after endotracheal tube insertion;Patient comfortabilityTimepoint: During the procedure;Time taken for intubationTimepoint: During the procedure—

Countries

India

Contacts

Public ContactSurajit Chattopadhyay

Institute of Post Graduate Medical Education & Research

surajit.chattopadhyay270@gmail.com8100765206

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026