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Comparison between thiopentone and propofol regarding hemodynamics during induction of GA

Comparative study between intravenous Thiopental sodium and Propofol for hemodynamic response during induction of General anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/048906
Enrollment
80
Registered
2023-01-11
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj Thiopental sodium: 3-5 mg/kg intravenous injection to be given as induction agent during induction of general anaesthesia Control Intervention1: Inj Propofol: 2.5-3 mg/kg intravenou

Sponsors

Health and family welfare department
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I, II, III undergoing elective surgery under general anaesthesia Giving positive consent Undergoing surgical procedures - general surgery urosurgery orthopaedic surgery neurosurgery ENT surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: Patients giving negative consent Age 60 years Patient having recent URTI, any drug allergy Anticipated difficult airway, restricted mouth opening, h/o regurgitation Patients having neuromuscular disorder and neurological symptoms, pathology of oropharynx, neck and upper GIT Patients having hypertension Pregnancy Patients on medication affecting heart rate and blood pressure

Design outcomes

Primary

MeasureTime frame
To analyse how effective Propofol and Thiopental sodium are to maintain Hemodynamic stability during induction and to compare changes in pulse rate, diastolic blood pressure, systolic blood pressure, mean arterial pressure of the two groupsTimepoint: All parameters mentioned above are monitored at 0, 1,3,5,10,15 minutes after induction

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Reema Vansola

BJMC Ahmedabad

reema.vansola@gmail.com9925114116

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026