Efficacy between IV labetolol vs oral nifedipine in acute severe hypertension in pregnancy

IV labetolol vs oral nifedipine in acute severe hypertension of pregnancy-A Randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/01/048873

Enrollment

148

Registered

2023-01-10

Start date

Unknown

Completion date

Unknown

Last updated

2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O122- Gestational edema with proteinuria

Interventions

Intervention1: Labetolol and Nifidipine: After explaining the condition of the patient and getting prior informed consent, all the patients will be randomly divided into two groups Group A and B. â?¢

20,40,80mmhg) at 15minutes interval until target BP achieved.

Eligibility

Inclusion criteria

Inclusion criteria: All singleton pregnant women of 20weeks gestation or more presenting with Acute severe hypertension, pre-eclampsia, Eclampsia & HELLP syndrome

Exclusion criteria

Exclusion criteria: Bronchial asthma , Cardiac failure , Cardiac rhythm abnormalities , Chronic hypertension , Multiple pregnancy

Design outcomes

Primary

Measure	Time frame
To achieve a target blood pressure of less than 140/90 mmhgTimepoint: 15-20mins or 20-30mins	—

Secondary

Measure	Time frame
not applicableTimepoint: not applicable	—

Countries

India

Contacts

Public ContactGayathri PT

KLE university

kamalpatil1967@yahoo.co.in9845565454

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026