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Evaluation of the lung function using a new calculated index from ventilator settings, blood oxygen values, supplemented Oxygen fraction during assisted breathing and observed lung compliance, aiding early ventilator weaning and facilitating tracheal extubation after heart surgeries.

â??Role of the new PaO2/ (FiO2 X PEEP) [P/FP] ratio and Static lung compliance in fast tracking Cardiac Surgeryâ?? - PEEP - Postive End Expiratory Pressure

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/01/048822
Enrollment
120
Registered
2023-01-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Control Intervention1: NIL: NIL

Sponsors

HARI DEV J J
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Elective CABG, Aortic and Mitral valve surgeries with median sternotomy and two-lung ventilation. 2. Adult patients (age 18 years or older) 3. Ability to provide informed consent

Exclusion criteria

Exclusion criteria: 1. Non-elective cardiac surgery 2. Patientâ??s refusal 3. Pregnancy 4. Thoracotomy approach, with one-lung ventilation 5. Previous pulmonary resection 6. Patients with acute kidney injury requiring dialysis 7. Patients with chronic kidney insufficiency (stage III or greater) 8. Patients already intubated before arrival in operating Théâtre.

Design outcomes

Primary

MeasureTime frame
Primary objectives: 1.To evaluate the usefulness of the PaO2/FIO2Ã?PEEP ratio and Static lung compliance for predicting oxygenation status and ventilatory requirements after cardiac surgery in order to provide a potential tool and value for immediate postoperative assessment in fast-tracking. Timepoint: 7 months—

Secondary

MeasureTime frame
Secondary objectives: (d) To test the value of P/FP ratio and Static lung Compliance at 1hr post ICU admission in predicting postoperative pulmonary complications. (e) Evaluating P/FP ratio and Static lung compliance in predicting post extubation - NIV (Non Invasive Ventilation) requirement and duration. (f) To assess the correlation between P/FP ratio and Static lung compliance.Timepoint: 7 months—

Countries

India

Contacts

Public ContactHARI DEV J J

Sree Chithra Tirunal Institute of Medical Science and Technology

subin@sctimst.ac.in8289983726

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026