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Mifepristone versus dinoprostone gel for cervical ripening prior to induction of labour

Mifepristone versus Dinoprostone gel for pre induction cervical ripening. A randomized controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/048774
Enrollment
105
Registered
2023-01-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: miferistone for cervical ripening: It includes 35 women admitted in IPD of the department of Obstetrics and Gynecology AIIMS, Raipur fulfilling inclusion and exclusion criteria. They wi

Sponsors

chethan k m
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria - All the pregnant women admitted in obstetric ward who are planned for induction of labour and in which delivery can be waited for > 24 hours “with ? 1. Maternal age group between 18-40 years of age. 2. Parity less than or equal to 2. 3. Singleton pregnancy. 4. Vertex presentation. 5. Gestational age between 34 to 42 weeks. 6. Pre-induction Bishop’s score less than 4. (according to modified Bishops score) 7. With intact membranes. 8. Patients with reassuring NST. 9. Willing to participate for study.

Exclusion criteria

Exclusion criteria: Exclusion Criteria – 1. Women with known hypersensitivity reaction to mifepristone and prostaglandins. 2. Women with contraindications for labour induction. a. Women with ante partum haemorrhage. b. Women with cephalopelvic disproportion. c. Estimated fetal weight > 4 kg. 3. Medical problems like known case of impaired renal and hepatic functions. 4. Refusal by consultant incharge of the patient or patient herself to participate in study.

Design outcomes

Primary

MeasureTime frame
1.IMPROVMENT IN BISHPOS SCORE AFTER 24 HR FROM THE TIME OF ADMINISTRATION OF DRUGTimepoint: 1. 24 hours from the time of administration of drug

Secondary

MeasureTime frame
1.TO STUDY IMPROVEMENT IN BISHOPS SCORE 24 HR FROM DRUG ADMINISTRATION IN PREVIOUS LSCS PATIENTSTimepoint: after 24 hours from the time of administration of the drug

Countries

India

Contacts

Public Contactchethan k m

AIIMS Raipur

drsaritaagrawal@aiimsraipur.edu.in8518881744

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026