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Comparison of post operative pain relief efficacy of adjuvant drugs (clonidine and buprenorphine) with local anaesthetic drug(bupivacaine ) used in epidural anaesthesia in lower abdominal and lower limb surgeries.

Comparative post operative analgesic efficacy of epidural clonidine and buprenorphine with bupivacaine in lower abdominal and lower limb surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/048761
Enrollment
140
Registered
2023-01-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Clonidine: Clonidine , an α2 agonist will be used as an adjuant with bupivacaine in epidural anaesthesia in lower abdominal and lower limb surgeries. Postoperatively a single bonus do

Sponsors

Goa Medical College and Hospital ,Bambolim
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 & 2 patients,undergoing lower abdominal and lower limb surgeries. Patients giving consent.

Exclusion criteria

Exclusion criteria: Patients having hypersensitivity to study drugs. Patients who are known cases of angina, cardiac failure, arrhythmias. Drug abusers. Patients having psychiatric or neurological illness

Design outcomes

Primary

MeasureTime frame
Comparison of post operative analgesic efficacy of epidural clonidine with bupivacaine and buprenorphine with bupivacaine. Timepoint: vitals and pain scores monitored at 5 minutes,10 minutes,15 minutes,30 minutes,45 minutes and 60 minutes of administration of the study drugs followed by hourly monitoring till 6 hours followed by 6 hourly monitoring till 24 hours.

Secondary

MeasureTime frame
Adverse effects of epidural clonidine and buprenorphine.Timepoint: Percentage of incidence of adverse effects in each groups.

Countries

India

Contacts

Public ContactDr Viraj Namshikar

Goa University

viraj1827@gmail.com9823512436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026