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To compare two different treatment modalities in the treatment of alopecia areata

Comparative study of platelet rich plasma vs intralesional triamcinolone acetonide in the treatment of alopecia areata

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/048750
Enrollment
60
Registered
2023-01-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj triamcinolone acetonide: Inj triamcinolone acetonide to be injected at 0
6 weeks. Intervention2: injection platelet rich plasma: Injection platelet rich plasma given 3weekly for 3 doses in the treatment of localized alopecia areata of the scalp (aged 18-60 years) Control I

Sponsors

DR BSA MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Clinically diagnosed cases of alopecia areata of scalp aged 18-60 years with • Patients with 1-5 patches of hair loss. • Patient who gives consent for the study

Exclusion criteria

Exclusion criteria: Patients with alopecia totalis,alopecia universalis or Ophiasis. 1.Patient with history of diabetes,hypertension,thromboembolism,bleeding disorders,abnormal coagulogram, patient already on steroid therapy,keloidal tendencyetc. 2.Pregnant or lactating female. 3.Patient with any active skin infectionat the site of hair loss. 4.Patient who has taken topical or intralesional treatment within last 1 month and oral treatment within last 3 months for alopecia areata.

Design outcomes

Primary

MeasureTime frame
To compare the SALT Score to prove efficacy of platelet rich plasma vs.intralesional triamcinolone acetonide (10mg/ml) given 3weekly for 3 doses in the treatment of localized alopecia areata of the scalp (aged 18-60 years) as assessed by mean SALT scoring.Timepoint: 3,6 and 9 weeks follow up

Secondary

MeasureTime frame
1.To compare the efficacy as per Hair Regrowth Grade Scale (HRG) at 3, 6 & 9 weeks between two groups. 2.To compare VAS for pain due to intralesional injection between the two groups. 3.To compare the patient satisfaction score between two groups. 4.To compare the relapse rates at 18 weeks in both groups. 5.To compare the side effect profile between two groups.Timepoint: 0,3,6,9,18 WEEKS

Countries

India

Contacts

Public ContactYashika Sethi

Dr. BSA Hospital

VIVEKSAGAR_SAGAR@YAHOO.CO.IN9210338647

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026