Health Condition 1: C228- Malignant neoplasm of liver, primary, unspecified as to type
Conditions
Interventions
Intervention1: 2% lignocaine: upto 5ml/kg of 2% lignocaine will be infiltrated at liver capsule over the subcapsular lesion.
Duration of procedure 20 min
Control Intervention1: No intervention at live
Sponsors
Rajiv Gandhi Cancer Institute and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA Grade(I-III) 2.All patients with Subcapsular Liver lesion posted for RFA/microwave ablation
Exclusion criteria
Exclusion criteria: 1.Patients with history of M.I, Arrythmia or any other cardiac morbidity. 2.Difficult airway 3.Deranged liver function test and coagulation profile 4.Chronic alcoholic 5.History of any cognitive or psychiatric illness 6.Patients on medication for chronic pain 7.Allergy to Lignocaine 8.Patient on ventilator, poor GCS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To achieve a visual analogue pain score of 3 during the procedure.Timepoint: 0 min Baseline preprocedure 2 min after start of procedure 6 min after start of procedure 8 min after start of procedure 10 min after start of procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial oxygen saturationTimepoint: 0 min Baseline preprocedure 2 min after start of procedure 6 min after start of procedure 8 min after start of procedure 10 min after start of procedure 0 hour immediate post procedure 6 hour post procedure 10 hour post procedure 14 hour post procedure;Heart RateTimepoint: 0 min Baseline preprocedure 2 min after start of procedure 6 min after start of procedure 8 min after start of procedure 10 min after start of procedure 0 hour immediate post procedure 6 hour post procedure 10 hour post procedure 14 hour post procedure ;Mean arterial pressureTimepoint: 0 min Baseline preprocedure 2 min after start of procedure 6 min after start of procedure 8 min after start of procedure 10 min after start of procedure 0 hour immediate post procedure 6 hour post procedure 10 hour post procedure 14 hour post procedure;Respiratory rateTimepoint: 0 min Baseline preprocedure 2 min after start of procedure 6 min after start of procedure 8 min after start of procedure 10 min after start of procedure 0 hour immediate post procedure 6 hour post procedure 10 hour post procedure 14 hour post procedure;To compare the Observer assessment of alertness scoreTimepoint: 0 min Baseline preprocedure 2 min after start of procedure 6 min after start of procedure 8 min after start of procedure 10 min after start of procedure 0 hour immediate post procedure 6 hour post procedure 10 hour post procedure 14 hour post procedure;To compare the patient, anaesthetist and Interventional radiologist satisfaction score.Timepoint: Post procedure;To compare visual analogue score in post procedure periodTimepoint: 0 hour immediate post procedure 6 hour post procedure 10 hour post procedure 14 hour post procedure | — |
Countries
India
Contacts
Public ContactDr Nitesh goel
Rajiv Gandhi Cancer Institute and Research Centre
Outcome results
None listed