Health Condition 1: S026- Fracture of mandible
Conditions
Interventions
Intervention1: Calcitonin Nasal Spray: Salmon Calcitonin Nasal Spray 200 IU (1 puff daily) for 30 days
Control Intervention1: No nasal spray: No placebo is given
Sponsors
Dr Firdous Abdul Sathar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with isolated mandibular fracture involving symphysis, parasymphysis, body, or angle 2. The age range of 18-50 years 3. Patients categorized as ASA I Status 4. Patients tolerant to the calcitonin nasal spray
Exclusion criteria
Exclusion criteria: 1. Comminuted mandibular fractures 2. Patients with any bony pathologies or thyroid dysfunctions 3. Individuals categorized under ASA II, III, or IV 4. Patients who have negative surgical outcomes such as postoperative malocclusion, interfragmentary mobility, or step deformity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To evaluate the efficacy of salmon calcitonin on postoperative pain in mandibular fracture patients. 2. To assess the change in levels of plasma osteocalcin after administration of salmon calcitonin. 3. To evaluate the bone density following open reduction and internal fixation of mandibular fractures after administration of salmon calcitonin. Timepoint: 1.Visual Analogue Scale on 1st,3rd, and 5th post-operative days. 2. Serum osteocalcin levels before surgery and after 4 weeks. 3. Density of bone at fracture site by CBCT scans taken at 2 weeks and 4 weeks postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess a better quality of life in these patients by fore said parameters.Timepoint: Follow up for 1 month. | — |
Countries
India
Contacts
Public ContactDr Firdous Abdul Sathar
YENEPOYA DENTAL COLLEGE, MANGALORE, KARNATAKA
Outcome results
None listed