Health Condition 1: F20- Schizophrenia
Conditions
Interventions
Intervention1: Fluoxetine: Minimum of 70 patients (35 in each group) with a diagnosis of Schizophrenia as per ICD 11 with co morbid Obsessive Compulsive Symptom/Disease as per Yale Brown Obsessive Com
Sponsors
Government Medical College and Hospital Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1 Patients with diagnosis of Schizophrenia as per ICD 11 and presence of Obsessive Compulsive Symptoms as per Yale Brown Obsessive Compulsive Symptom Checklist 2 Patients having capacity as per Section 4 of Mental Health Care Act 2017 to give written consent or Nominated Representative agreeing to give written consent when the patient does not have adequate capacity 3 Patients on stable dose of antipsychotic medications for the past 3 months (no more than 50% reduction or increase in antipsychotic medications) 4 Age 18 to 65 years 5 Any gender
Exclusion criteria
Exclusion criteria: 1 Patients with active substance use disorder within the past 6 months (fulfilling the ICD 11 criteria for substance dependance) except caffeine and nicotine 2 Patients with any acute medical or surgical illness or receiving concomitant medications with contraindications to Fluoxetine 3 Pregnant and Lactating patients 4 Actively suicidal patients or those having high suicidal risk currently 5 Patients already on SSRI and/or Clomipramine for any other co morbid psychiatric condition 6 Patients receiving non pharmacological intervention like ERP or CBT
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the response to treatment with Fluoxetine in persons with Schizophrenia having Obsessive Compulsive SymptomsTimepoint: Assessment shall be done at baseline, 2 weeks, 4 weeks, 6 weeks and 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 To study the association among various socio-demographic and clinical correlates in persons with Schizophrenia having OCS and OCD 2 Compare pre and post treatment changes in OCS and other symptom profile in SchizophreniaTimepoint: Baseline, 8 weeks | — |
Countries
India
Contacts
Public ContactDr Sushmita Bhattacharya
Government Medical College and Hospital, Sector 32, Chandigarh
Outcome results
None listed