Comparing oxygenation between oxygen given through two devices

A prospective randomized controlled study on pre-oxygenation using high-flow nasal oxygen vs. tight facemask during rapid sequence induction

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/01/048705

Enrollment

100

Registered

2023-01-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring Health Condition 2: K358- Other and unspecified acute appendicitis

Interventions

Intervention1: High flow nasal oxygen: Preoxygenation using HFNO 50L/min 90% FiO2 For 3 min after saturation reads 100% on Pulseoximeter. Total duration of maximum 10 min Control Intervention1: Tight

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing general Anaesthesia ASA 1& 2

Exclusion criteria

Exclusion criteria: Pregnancy Difficult intubation Emergency cases Not willing to participate

Design outcomes

Primary

Measure	Time frame
Difference in PaO2 levelsTimepoint: Baseline, After intubation after confirming the first ETCO2 reading. (Max 10 min)	—

Secondary

Measure	Time frame
Bradycardia Tachycardia ECG changes Hypotension DesaturationTimepoint: During intubation for 90-150 sec	—

Countries

India

Contacts

Public ContactDr B Gayathri

SRM MCH RC

gayathrii.r@gmail.com9500092905

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026