Health Condition 1: J399- Disease of upper respiratory tract, unspecified
Conditions
Interventions
Intervention1: Role of dexamthasone in post extubation stridor: Group A will receive intravenous Dexamethasone 4 dosage at 0.15mg/kg/dose q6hourly 24 hours prior to extubation and 2 dosage q6hourly af
Sponsors
Lady Hardinge Medical College and Kalawati Saran Children Hospital, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 1 months to 18 years requiring mechanical ventilation for more than 48 hours and planned for extubation
Exclusion criteria
Exclusion criteria: Pre-existing upper airway anomalies Previous tracheal intubation or tracheostomy Contraindications for steroid therapy (Upper GI Bleed, Hypertension, hyperglycemia) Children who had previously received steroids for more than 7 days (I.e. Patients on steroid therapy) Previous extubation failure during PICU stay
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of children who developed post extubation stridor in children receiving mechanical ventilation for more than 48 hoursTimepoint: mechanical ventilation for more than 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of children developing side effects due to IV dexamethasone in both the groupsTimepoint: mechanical ventilation for more than 48 hours;Proportion of patients requiring adrenaline neb and reintubation following extubationTimepoint: mechanical ventilation for more than 48 hours;Risk factors for development of post extubation stridorTimepoint: mechanical ventilation for more than 48 hours;Time to recovery from post extubation stridor/ post extubation airway obstruction in both the groupsTimepoint: mechanical ventilation for more than 48 hours | — |
Countries
India
Contacts
Public ContactPriyanshu
Lady Hardinge Medical College and Kalawati Saran Children Hospital, New Delhi.
Outcome results
None listed