Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Group 1 - Drug Loaded iPRF(Injectable Platelet Rich Fibrin ): After Scaling and Root Planing (SRP), this group will be treated with Doxycycline loaded iPRF for localised periodontal poc
Sponsors
Thamaraiselvan Murugan
Eligibility
Inclusion criteria
Inclusion criteria: Patient selection was done according to the 2017 World Work shop on the Classification of Periodontal and PeriÂImplant Diseases and Conditions. Patients with Stage II Grade B periÂodontitis (moderate periodontitis) were included. Patients having a minimum of 2 sites with probing depth (PD) > 5 mm and clinical attachment loss (CAL) >4 mm with horizontal bone loss at 2 different quadrants, and requiring nonÂsurgical treatÂment were considered as eligible for the study.
Exclusion criteria
Exclusion criteria: Patients with habits, like smoking, tobacco chewing or alcohol consumption, having uncontrolled diabetes, hyper tension or immunocompromised conditions, pregnant women or lactating mothers, nonÂcompliant or physically challenged people, and those who were not able to main tain oral hygiene or be followed up at a recall visit
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing Depth (PD), Clinical Attachment Level (CAL), Gingival Index (GI), plaque Index (PI),Timepoint: Baseline (BL), 6th week, 12th week | — |
Secondary
| Measure | Time frame |
|---|---|
| Salivary Glutathione levels, Salivary collagenase levels, p.gingivalis levelsTimepoint: Baseline (BL), 6th week, 12th week | — |
Countries
India
Contacts
Public ContactThamaraiselvan Murugan
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences
Outcome results
None listed