Health Condition 1: E11- Type 2 diabetes mellitus
Conditions
Interventions
Intervention1: Dapagliflozin add-on to metformin in type 2 diabetes mellitus: Dapagliflozin add-on to metformin in type 2 diabetes mellitus those who are inadequatively controlled on a stable dose of
Sponsors
Aditya kumar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with T2DM inadequately controlled with Metformin 1-2 gm per day 2. Those patients who are unable to tolerate further increase in further dose of Metformin 3. Patients aged 30 to 70 years 4. HbA1C 7.0% to 9.0%
Exclusion criteria
Exclusion criteria: 1. Patient who are on insulin 2. Patient described any other anti diabetic medication after adding Dapagliflozin to Metformin 3. Patients in which dose of metformin has to be altered 4. Patients with renal insufficiency (GFR lress than 30ml/min/1.73m2) 5. Patients who are known case of urinary tract infection , structural abnormalities of urinary tract. 6. Patients with acute complications of diabetes mellitus 7. Patients with hypersensitivity to drug
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To access the effect of Dapagliflozin on: 1. Glycemic parameters 2. Lipid profile 3. Bmi 4. Blood pressure 5. To study the efficacy of Dapagliflozin Timepoint: Selected patients will be evaluated for Blood Pressure, Body weight, CBC, KFT, LFT, Lipid Profile, Urinary albumin creatinine ratio (UACR), Urine R/m, Fasting Blood sugar, 2 hours Post parandial Blood sugar and HbA1c on first visit. These patients will be followed up in OPD every month till 3 months. At the end of 3 months, Blood Pressure, Body weight, CBC, KFT, LFT, Lipid Profile, Fasting Blood sugar, 2 hours Post prandial Blood sugar and HbA1c will be assessed. | — |
Secondary
| Measure | Time frame |
|---|---|
| nilTimepoint: nil | — |
Countries
India
Contacts
Public ContactDr Aditya kumar
Varunarjun medical college and rohilkhand hospital
Outcome results
None listed