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Study on the effect of reducing agents on nicotine residues in smoker plasma sample

In-vitro assessment of the effect of reducing agent on the conversion of cotinine into nicotine from plasma samples from smokers

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/12/048600
Enrollment
25
Registered
2022-12-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: NIL: NIL

Sponsors

Sri Ramachandra Institute of Higher Education and Research DU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Chronic smoker 2. patients above 18 years old 3. consumer of other tobacco products such as chewed products, electronic cigarette, etc.

Exclusion criteria

Exclusion criteria: 1. Patients with no smoking effect 2. Pregnant women 3. Patients taken alcohol within 24 hours

Design outcomes

Primary

MeasureTime frame
The study will estimate the quantity of reducing agent required for the conversion of continuing (nicotine metabolite) to nicotine in plasma samples from smokers.Timepoint: 12 months—

Secondary

MeasureTime frame
Quantification of nicotine and cotinine using simultaneous method by using HPLCTimepoint: 6 months—

Countries

India

Contacts

Public ContactManish A

Sri Ramachandra Institute of Higher Education and Research, Chennai-600116

murugesan.a@sriramachandra.edu.in8870151588

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026