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Local anaesthetic with or without additive in fracture femur surgery

Evaluation of Analgesic efficacy of hyperbaric levobupivacaine with or without clonidine in patients undergoing surgery for fracture femur under subarachnoid block : a randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048579
Enrollment
30
Registered
2022-12-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S729- Unspecified fracture of femur

Interventions

Intervention1: Subarachnoid Block: Spinal anaesthesia will be given in sitting position in L3-L4 space Control Intervention1: Hyperbaric Levobupivacaine with clonidine: Group-LC:15mg of 0.5% hyperbari

Sponsors

University College Of Medical Sciences and Guru Teg Bahadur Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consenting patients belonging to ASA grade I or II, between 18-65 years of age and height 150-180 cm, about to undergo surgery for fracture femur requiring intramedullary nail under subarachnoid block will be included in the study.

Exclusion criteria

Exclusion criteria: • Patients with contraindication to subarachnoid block: infection at injection site, coagulopathy, space-occupying lesion, increased intracranial tension, known case of seizure disorder, pre-existing neurological deficit, and spine deformity. • History of allergy to any drug being used in the study. • Pregnant patients. • Known case of hepatic and renal disease, drug addicts and chronic alcoholics. • Patients who are on antiarrhythmic drugs.

Design outcomes

Primary

MeasureTime frame
Duration of effective analgesiaTimepoint: Time from the subarachnoid block to the time of VAS â?¥ 3

Secondary

MeasureTime frame
Sensory block, Motor block, Hemodynamic changes,Sedation score,Ancillary observationsTimepoint: 0,2,4,6,8,10,15,20,25,30,45,60,90,120,150,180,210,240 min after the spinal anaesthesia

Countries

India

Contacts

Public ContactDr Rajesh Singh Rautela

University College Of Medical Sciences and Guru Teg Bahadur Hospital

rsramb@gmail.com9868399699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026