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Assessing effect of Sugammadex vs neostigmine for reversing rocuronium induced block

Sugammadex vs neostigmine for reversing rocuronium induced block; A prospective randomised trial in Indian population

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048551
Enrollment
30
Registered
2022-12-27
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Sugamadex: Sugammadex 2mg/ kg will be administered for the reversal of rocuronium, monitored upto 30 min for complete recovery Control Intervention1: Neostigmine: Neostigmine 0.05mg/kg

Sponsors

Pt BD Sharma, PGIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients 1. aged between 18-60 years of 2. either sex, belonging to American Society of Anesthesiologists 3. (ASA) physical status I or II scheduled for elective surgery requiring general anaesthesia and 4. secured airway will be enrolled in the study

Exclusion criteria

Exclusion criteria: 1. Refusal to give consent 2.Patients with disorder of cardiovascular, hepatic, renal or neuromuscular system 3.Pregnant and lactating ladies 4.Known allergy to study drug

Design outcomes

Primary

MeasureTime frame
quality of recovery from neuromuscular blocker by using neostigmine or sugamadex, at30 sec,1 min, 2 min, 4 min NMB reversal to recovery of the TOF ratio to 0.9 •Extubation time Timepoint: quality of recovery from neuromuscular blocker by using neostigmine or sugamadex, at 30 sec, 1 min, 2 min, 4 min from NMB reversal to recovery of the TOF ratio to 0.9 •Extubation time

Secondary

MeasureTime frame
Aldrette scoreTimepoint: in recovery period

Countries

India

Contacts

Public ContactPrashant Kumar

Pt BD Sharma PGIMS, Rohtak

pk.pgims@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026