Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Nebulized Dexmedetomidine: Nebulization with Dexmedetomidine at a dose of 1 μg/kg (mixed with normal
saline to a total volume of 5 ml) given 30 minutes before induction of general anes
Sponsors
Dheeraj Gopal Ravindran
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade I or II fit patients. 2. Patients aged between 18 and 60 years of age. 3. Patients undergoing surgeries under general anaesthesia. 4. Haemodynamically stable patients with all routine investigations within normal limits and without any comorbidities. 5. Written informed consent from the concerned patient.
Exclusion criteria
Exclusion criteria: 1. Patients who are not willing to participate in the study. 2. Patients with ASA grade III and above physical status. 3. Patients who are aged less than 18 and more than 60 years of age. 4. Patients who are posted for emergency procedures. 5. Patients with known allergy to the study drugs. 6. Patients with difficult intubation. 7. Patients who are obese. 8. Patients who have psychiatric, neurological, neuromuscular or cardiovascular disease or impairment of hepatic or renal function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effects of preoperative dexmedetomidine nebulisation in blunting the stress response to laryngoscopy and intubation.Timepoint: During intubation till 10 minutes after intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To study any adverse effects from preoperative dexmedetomidine nebulisation.Timepoint: Any time during and after nebulization of dexmedetomidine | — |
Countries
India
Contacts
Public ContactDheeraj Gopal Ravindran
Dr. D. Y. Patil Medical College, Hospital & Research Centre
Outcome results
None listed