FindTrial
Sign In

To assess the efficiency of 2 different pain killers, ibuprofen and etoricoxib on its ability to reduce the pain and inflammation during root canal treatment in teeth having pulplal inflammation.

Comparative evaluation of the effect of pre-operative Ibuprofen vs Etoricoxib on interlukin-6 and intra-operative pain in symptomatic irreversible pulpitis-An in-vivo study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048521
Enrollment
60
Registered
2022-12-27
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Etoricoxib 90mg A selective COX-2 inhibitor: Dose: 90 Mg Frequency: Only 1 tablet one hour prior to procedure. Route of administration: Oral Duration of therapy: 45 minutes for root c

Sponsors

Dr Adarsha M S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA class 1 (a normal healthy patient fit, non-obese, non-smoking) 2. Permanent mandibular molars of both right and left quadrant. 3. Teeth with clinical diagnosis of symptomatic irreversible pulpitis. 4. Patients who had not taken any analgesics at least a day before the root canal procedure.

Exclusion criteria

Exclusion criteria: 1. Any teeth with diagnosis of pulpal necrosis 2. Teeth which are diagnosed with periodontal problems 3. Teeth which were previously treated with root canal procedure 4. Patients who cannot tolerate or who are allergic to ibuprofen and etoricoxib 5. Patients with pre-existing systemic conditions.

Design outcomes

Primary

MeasureTime frame
To assess and compare the effect of pre-operative ibuprofen and etoricoxib on interlukin-6 levels in symptomatic irreversible pulpitis.Timepoint: Baseline: the outcome is assessed while performing the treatment procedure.—

Secondary

MeasureTime frame
Secondary outcome in this study will be measured by asking the patients to rate the pain on Heft Parker visual analogue scale â?¢ The scale is divided into 4 categories: 1. no pain corresponded to 0 mm; 2. faint, weak, or mild pain corresponded to 0â??54 mm; 3. moderate pain corresponded to 55â??114 mm; and 4. strong, intense, and maximum possible pain corresponded to more than 114 mm Timepoint: Intra-operative,30 min—

Countries

India

Contacts

Public ContactDr Adarsha M S

Vokkaligara sangha dental college and hospita

adarshgowda11@gmail.com9844474688

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026