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Comparison between Dexmedetomidine and fentanyl on intraoperative neuromuscular monitoring using propofol based total intravenous anesthesia regimen in spine surgeries.

Dexmedetomidine versus fentanyl in intraoperative neuromuscular monitoring using propofol based total intravenous anesthesia regimen in spine surgeries.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048497
Enrollment
60
Registered
2022-12-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: G328- Other specified degenerative disorders of nervous system in diseases classified elsewhere

Interventions

Intervention1: intravenous propofol (5â?? 10 mg/kg/h) and dexmedetomidine (0.5â??0.7 mcg/kg/h) in group D: intravenous propofol (5â?? 10 mg/kg/h) and dexmedetomidine (0.5â??0.7 mcg/kg/h) in group D st

Sponsors

Mahatma Gandhi medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA physical status I, II 2.Aged 18-65 years scheduled for major spine surgeries 3.Both male and female

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.History of allergy to the study drug 3.Impaired renal/hepatic function 4.History of allergy to study drug 5.Severe cardiovascular disease

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the effect of dexmedetomidine and fentanyl on intraoperative hemodynamic parameters and their interference with MEP.Timepoint: BASELINE,INTUBATION5 MINS,10 MINS,20 MINS,30 MINS,60 MINS,120 MINS,150MINS,180 MINS,210 MINS,240 MINS,270 MINS,300 MINS,330 MINS,360 MINS—

Secondary

MeasureTime frame
â?¢ To assess the quality of surgical field.Timepoint: feedback from surgeon at the end of surgery—

Countries

India

Contacts

Public ContactMedha Bhardwaj

Mahatma Gandhi hospital

drsunitakhs@yahoo.com998890238

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026