Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Magnesium sulphate: Intravenous infusion of magnesium sulphate
at a dose of 30mg/kg in 100 ml solution over 20 minutes before intubation.
Intervention2: Magnesium sulphate: Magnesium su
Sponsors
Department of anaesthesia and critical care
Eligibility
Inclusion criteria
Inclusion criteria: Both male and female between the age of 18 to 65 will be included.
Exclusion criteria
Exclusion criteria: History of hypersensitivity to magnesium sulphate. Anticipated difficult airway. Patients on steroid therapy. Patients on psychiatric medication. Pregnancy Anticipated major fluid shift surgeries.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Hemodynamic parameters following laryngoscopy and intubation in terms of: 1)Heart rate 2) Systolic blood pressure 3)Diastolic blood pressure 4)Mean arterial pressureTimepoint: At different time intervals: Baseline (T0) Post intervention/pre-induction(T1) Just before laryngoscopy(T2) 1 min.post-intubation(T3) 3 min.post-intubation(T4) 5 min.post-intubation(T5) 10 min.post-intubation(T6) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Serum Cortisol level 2)Serum magnesium levelTimepoint: 1)Serum Cortisol level: Baseline Post intubation (15 min) 2)Serum magnesium level: Baseline Post intubation (15 min) | — |
Countries
India
Contacts
Public ContactAmita Gupta
Vardhman Mahavir Medical College and Safdarjung hospital
Outcome results
None listed