Health Condition 1: L988- Other specified disorders of the skin and subcutaneous tissue
Conditions
Interventions
Intervention1: Capsule Curcumin 500 mg: Capsule form-Content punctured and applied by patient.
Route of administration- Topical
Frequency - 3 times a day
Duration - 3 months
Control Intervention1: Ret
Sponsors
Sri Rajiv Gandhi College of dental Sciences and hospital
Eligibility
Inclusion criteria
Inclusion criteria: Age > 20 years Patient with cessation of habit 1 month before intervention. Patients reporting to the department of oral and maxillofacial surgery with clinical sign and histologically proven premalignant lesions. Patients with early stage lesion Patients willing to be a part of the study and giving consent for the same
Exclusion criteria
Exclusion criteria: 1)Patient with h/o topical therapy to oral lesion. 2)Patients with hypersensitivity to drug 3)Patients reporting to the department of oral and maxillofacial surgery with clinical sign and histologically proven premalignant lesions. 4)Pregnancy 5)Patients with advanced stage lesion 6)Patients with h/o reported adverse effects to treatment with retinoic acid and curcumin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Pain- Visual analog scale 2)Burning sensation of the lesion 3)Change in size of lesionTimepoint: 1)Baseline 2)During application period- 15 days once- upto 1 month Every month once- upto 3 months 3)During followup- Every month once- upto 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effectsTimepoint: Single visit | — |
Countries
India
Contacts
Public ContactDr Hemavathi U
Sri Rajiv Gandhi College of Dental Sciences
Outcome results
None listed