None listed
Conditions
Interventions
Intervention1: Inj Ketamine: Low dose ketamine bolus
0.1mg/kg will be administered iv
before giving spinal
anaesthesiaa followed by
infusion of ketamine 0.1
ml/kg/hr iv throughout the period
of surger
Sponsors
Saveetha medical college and hospital
Eligibility
Inclusion criteria
Inclusion criteria: All patients of age group 18 to 50 years of ASA 1 and 2 undergoing abdominal and lower limb surgeries under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: 1) Any contraindication or un willingness for spinal anaesthesia. 2) Patients with BMI > 40 kg/m2 3) Patients with uncontrolled hypertension, risk of coronary or vascular disease. 4) Increased intraocular or intracranial pressure/glaucoma. 5) History of psychosis, convulsions, neuromuscular diseases. 6) Patients with hepatic or renal dysfunction 7.History of allergy to Ketamine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the incidence of Intraoperative shivering after administration of low dose Intravenous Ketamine and placebo. Timepoint: Grade of shivering intraoperatively will be assessed and recorded every 5 min for the initial 30 min followed by every 15 min till the end of surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Hemodynamics ((MAP, HR, RR, temperature and SPo2 2.Degree of sedation. 3.Incidence of post operative shiveringTimepoint: 1.will be assessed and recorded every 5 min for initial 30 min followed by every 15 min till the end of surgery and in post-operative period. 2.Assessed and recorded every 5 min for the initial 30 min followed by every 15 min till the end of surgery and also for 2 hours post operatively. 3.Grade of shivering assessed every 30 min for 2 hours postoperatively. | — |
Countries
India
Contacts
Public ContactSuryaR
Saveetha medical college and hospital
Outcome results
None listed