FindTrial
Sign In

Comparision of inhalational dexmedetomidine inhalation with inhalation lignocaine for Controlling Blood pressure and heart rate during intubation

Comparison of nebulized dexmedetomidine and nebulized lignocaine in blunting the hemodynamic response to laryngoscopy and endotracheal intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048464
Enrollment
135
Registered
2022-12-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring Health Condition 2: 4- Measurement and Monitoring

Interventions

Intervention1: Comparison of nebulized dexmedetomidine and nebulized lignocaine in blunting the hemodynamic response to laryngoscopy and endotracheal intubation: Comparison of nebulized dexmedetomidin

Sponsors

Department of Anaesthesiology and Critical care Pt BD Sharma PGIMS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA physical status grade I and II of age 18 to 60 years planned for surgery under general anesthesia with endotracheal intubation.

Exclusion criteria

Exclusion criteria: • Patients not consenting for study • Anticipated difficult airway • Pregnancy • Seizure disorders • Patients on antidepressants/antipsychotics/antihypertensive like beta blocker • BMI >30kg/meter square • Drug allergy • Patients with decreased autonomic control such as elderly, diabetic patients. • Patients with poor cardiopulmonary reserve • Renal disease

Design outcomes

Primary

MeasureTime frame
To compare nebulized dexmedetomidine and nebulized lignocaine in blunting the hemodynamic response to laryngoscopy and endotracheal intubation with respect to HR, MAP, SBP and DBP.Timepoint: baseline (Tb), before induction (T0), during laryngoscopy, during intubation and post intubation at 1, 3, 5 and 10 min (T1, T3, T5 and T10)—

Secondary

MeasureTime frame
To study side effects associated with use of nebulized dexmedetomidine and lignocaine.Timepoint: baseline (Tb), before induction (T0), during laryngoscopy, during intubation and post intubation at 1, 3, 5 and 10 min (T1, T3, T5 and T10)—

Countries

India

Contacts

Public ContactGeeta Ahlawat

PGIMS ROHTAK

drgeetasaroha@gmail.com9215810279

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026