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COMPARISON OF ANTIBACTERIAL EFFICACY OF DIFFERENT ROOT CANAL DISINFECTING AGENTS IN PRIMARY TEETH

COMPARATIVE EVALUATION OF ANTIMICROBIAL EFFICACY OF TINOSPORA CORDIFOLIA, SODIUM HYPOCHLORITE AND CHLORHEXIDINE GLUCONATE IN ROOT CANAL DISINFECTION OF PRIMARY TEETH: A CLINICAL STUDY

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048411
Enrollment
75
Registered
2022-12-22
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Tinospora Cordifolia ethanolic extract (2% and 3%): Group 2- Ethanolic extract of Tinospora Cordifolia of concentration 2% Group 3- Ethanolic extract of Tinospora Cordifolia of concnetr

Sponsors

Dr Shilpa S
Lead Sponsor
M R Ambedkar Dental College and Hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients who belonged to Frankelâ??s 3 and Frankelâ??s 4 behavioural rating scale. 2.Patients between the age of 4-9 years of both sexes with no history of systemic illness. 3.Teeth with carious pulpal involvement which are indicated for pulpectomy. 4.Teeth with at least 2/3rd of root length intact. 5.Teeth which are restorable. 6.Patients who wilfully give assent and for whom the parents or guardian will give the written informed consent to be a part of this study.

Exclusion criteria

Exclusion criteria: 1.Teeth with pre-shedding mobility or abnormal pathologic mobility. 2.Teeth with root resorption which is more than 1/3rd of the root length. 3.Teeth which are not resorbable. 4.Teeth which show perforation of the pulpal floor. 5.Teeth with interdental bone loss. 6.Teeth with pathologic lesions like radicular granuloma or cyst.12 7.Patient with special health care needs. 8.Patients who are not willing or for whom the parent or the guardian did not give the written informed consent for the treatment. 9.Patients who are suffering from any other debilitating systemic illness.

Design outcomes

Primary

MeasureTime frame
Antimicrobial efficacy of Tinospora cordifolia in root canal disinfection. The efficacy of the extract will be assessed by the antimicrobial evaluation of gram positive and gram negative ,aerobic and anaerobic microorganisms through suitable culture methodsTimepoint: Baseline: Before the intervention First time point: Immediately after the intervention Second time point: 3 days post intervention

Secondary

MeasureTime frame
Clinically there is no pain, pus discharge from the root canals post intervention Microbiologically there is decrease in the microbial count post intervention Timepoint: Baseline before the intervention First time line Immediately after the intervention Second timeline 3days post intervention

Countries

India

Contacts

Public ContactDr Shilpa S

M R Ambedkar Dental College and Hospital

jyothsnasrikanth@gmail.com9449819468

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026