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Two methods for extubation

To Compare the Efficacy of Alkalinised Intracuff 4% Lignocaine versus Intravenous 2% Lignocaine for emergence phenomenon during extubation in patients undergoing procedures under General Anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048359
Enrollment
60
Registered
2022-12-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 4% alkalanised lignocaine: Group A where patients will receive Alkalinized intracuff lignocaine 4% 2 ml 40 minutes before extubation. Control Intervention1: 2% lignocaine IV: Group B pa

Sponsors

Dr D Y Patil Vidyapeeth
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age between 20 to 60 years of either gender Patients who give informed consent and are willing to be a part of the study Patients undergoing elective craniotomies, oral and maxillary surgeries, thyroid surgeries. Patients who are ASA-1 or II fit.

Exclusion criteria

Exclusion criteria: Age less than 20 years or more than 60 years Patients with history of sore throat, or URTI. Patients with tracheal or laryngeal pathology or history of tracheostomy. Patients with asthma or chronic obstructive pulmonary disease. Patients allergic to local anaesthetics. Patients on beta-blocker therapy

Design outcomes

Primary

MeasureTime frame
Good extubation responseTimepoint: Baseline, 1 min, 2 min, 5 min 30 min

Secondary

MeasureTime frame
Smooth extubationTimepoint: At the time of extubation

Countries

India

Contacts

Public ContactDr Sonalika Tudimilla

Dr. D. Y. Patil Vidyapeeth

sona3668@hotmail.com9676989293

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026