Comparison of pain relief after surgery for lower back pain of a block named modified plain thoraco-lumbar interfascial plane block (TLIP) Vs modified thoraco lumbar interfascial plane block with a drug called dexmedetomidine as adjuvant in patients undergoing lumbar disc surgeries.

Comparison of analgesic efficacy of modified plain thoraco-lumbar interfascial plane block (TLIP) Vs modified thoraco lumbar interfascial plane block with dexmedetomidine as adjuvant in patients undergoing lumbar disc surgeries: A comparitive, randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/12/048350

Enrollment

Registered

2022-12-21

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: M512- Other thoracic, thoracolumbar andlumbosacral intervertebral disc displacement

Interventions

Intervention1: Addition of Dexmedetomidine to block: All patients in this group will recieve ultrasound guided modified TLIP block (bilateral administration of 0.25% Ropivacaine along with 0.5 ug/kg o

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients undergoing lumbar disc surgeries 2)ASA grade I-III 3)Age group 18-70 years for patients scheduled for lumbar disc surgeries

Exclusion criteria

Exclusion criteria: 1)Patient refusal 2)Previous lumbar spine surgery 3)Extensive lumbar spine surgeries like large tumor excisions, scoliosis correction or more than 2 level spine fixations. 4)BMI > 35 5)History of opioid tolerance 6)Contraindications to regional technique, eg- local infection, systemic infection, coagulopathy. 7)Allergy to any drugs used in the study 8)Pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
To assess total opioid consumption -Intraopertive plus total fentanyl consumption with patient controlled analgesia in postoperative period. Timepoint: Intraopertive plus postoperative period until 24 hours.	—

Secondary

Measure	Time frame
Intraoperative hemodynamics- response to surgical incisionTimepoint: Intraoperative period;Postoperative pain- Visual analog score at rest and on movement/coughingTimepoint: Postoperative period until 24 hours.;Time to first analgesic requirement after surgeryTimepoint: Postoperative period until 24 hours.;Incidence of drug related side effects in both groups Timepoint: Intraoperative and Postoperative period until 24 hours;Overall patient satisfaction scoreTimepoint: Intraopertive plus postoperative period until 24 hours.	—

Measure

Time frame

Intraoperative hemodynamics- response to surgical incisionTimepoint: Intraoperative period;Postoperative pain- Visual analog score at rest and on movement/coughingTimepoint: Postoperative period until 24 hours.;Time to first analgesic requirement after surgeryTimepoint: Postoperative period until 24 hours.;Incidence of drug related side effects in both groups Timepoint: Intraoperative and Postoperative period until 24 hours;Overall patient satisfaction scoreTimepoint: Intraopertive plus postoperative period until 24 hours.

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Countries

India

Contacts

Public ContactSiddhavivek Majage

All India Institute Of Medical Sciences, New Delhi

darlongv@yahoo.com9868397809

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026