A study to evaluate the effect of ropivacaine (local anaesthetic) with morphine for lower limb surgeries

A comparative study to evaluate the efficacy of hyperbaric ropivacaine with and without morphine for subarachnoid block in lower limb orthopaedic surgeries-A randomised controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/12/048348

Enrollment

Registered

2022-12-21

Start date

Unknown

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S90-S99- Injuries to the ankle and foot Health Condition 2: S70-S79- Injuries to the hip and thigh Health Condition 3: S80-S89- Injuries to the knee and lower leg Health Condition 4: O- Medical and Surgical Health Condition 5: O- Medical and Surgical Health Condition 6: S79- Other and unspecified injuries ofhip and thigh

Interventions

Intervention1: Hyperbaric ropivacaine with morphine: Patient will receive 0.75% hyperbaric ropivacaine with 100 microgram morphine as 0.1 ml.Total analgesic requirement in 36 hours will be recorded. C

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grade I and II 2.Lower limb orthopaedic surgeries

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Patient with spine deformity,localized sepsis and raised intracranial pressure 3.Impaired mentation,neurological,psychiatric,neuromuscular,cardiovascular,pulmonary,renal or hepatic disease 4.Allergy to drugs under study 5.Morbid obesity 6.Coagulation disorders

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of 0.75% hyperbaric ropivacaine with and without morphine in terms of duaration of analgesiaTimepoint: 36 hours	—

Secondary

Measure	Time frame
To compare sensory and motor blockade characteristics,hemodynamic parameters and side effectsTimepoint: Duration of motor block will be from onset to complete recovery and duration of sensory block will be two segment regression from maximum level achieved	—

Countries

India

Contacts

Public ContactGurinder kaur

BPS Government Medical College

sarv.mlb007@gmail.com09728800122

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026