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PRP in Recurrent Implantation Failure

Role of PRP on endometrial receptivity in Recurrent Implantation Failure

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048264
Enrollment
154
Registered
2022-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O090- Supervision of pregnancy with history of infertility

Interventions

Intervention1: Autologous PRP: The schedule of Autologous PRP installation will be on 10th day of estrogen therapy and 12th day of estrogen therapy . Control Intervention1: Conventional: Only estrogen

Sponsors

Indira IVF Hospital Pvt Ltd
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age 25â??40 years. 2.Body mass index (BMI) 18.5 to 29.9 kg/m2. 3.RIF is defined as no evidence of Gestational sac in TVS after 6 wks of gestation after transfer of >= 3 high-quality embryos in at least 3 fresh or frozen transfer cycles in an age group of 4.Grade of embryo 3/4/5/6/AA/AB/BA.

Exclusion criteria

Exclusion criteria: 1.Presence of endocrine disorders (uncontrolled diabetes mellitus / hyperprolactinemia, thyroid dysfunction) 2.Previous major uterine surgery 3.Previous hysteroscopic adhesiolysis 4.Hydrosalpinx 5.Fibroid uterus type 0,1,2 as per FIGO classification 6.Any fibroid >3.5 cm 7.Adenomyosis. 8.Thrombocytopenia (total platelet count 9.Abnormal uterine cavity on Hysteroscopy. 10.The patient is unlikely to be available for follow-up as specified in the protocol. 11.Chronic Liver Pathology leading to impaired coagulation profile.

Design outcomes

Primary

MeasureTime frame
Implantation rateTimepoint: Six weeks after ET

Secondary

MeasureTime frame
Biochemical pregnancyTimepoint: Four weeks after ET;Clinical PregnancyTimepoint: Six weeks after ET;DeliveryTimepoint: Twenty four weeks after ET;Live BirthTimepoint: Thirty six weeks after ET;Ongoing PregnancyTimepoint: Twelve weeks after ET

Countries

India

Contacts

Public ContactDr Nihar Bhoi

Indira IVF Hospital Pvt Ltd

drnihar.bhoi@indiraivf.in07205783512

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026