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Effect of vasopressin in sick babies with low blood pressure

Effect of vasopressin in refractory neonatal shock- Retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/12/048258
Enrollment
50
Registered
2022-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P299- Cardiovascular disorder originating in the perinatal period, unspecified

Interventions

None listed

Sponsors

Dr Anup Thakur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All neonates with refractory shock who received vasopressin infusion at least for 24 hours from January 2016 to May 2021 will be included.

Exclusion criteria

Exclusion criteria: Neonates with congenital heart diseases or other lethal anomalies and those in whom data retrieval is inadequate will be excluded.

Design outcomes

Primary

MeasureTime frame
1.Systolic, mean and diastolic blood pressure at baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy- Blood pressure recordings will be retrieved from nursesâ?? chart. Invasive blood pressure readings will be considered whenever available. 2.Heart rate at baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy. 3.Urine output at baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy. 4.Biochemical parameters such as pH, bicarbonate levels, base deficit, lactate and sodium levels before and in first 72 hours of vasopressin administration. Worst parameters will be taken. 5.Inotrope score at baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy. 6.Oxygenation index at baseline and during first 72 hours of vasopressin therapy. Worst parameters will be taken. Timepoint: baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy

Secondary

MeasureTime frame
not applicableTimepoint: not applicable

Countries

India

Contacts

Public ContactDr Anup Thakur

Sir Ganga Ram Hospital

dr.thakuranup@gmail.com8800565956

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026