Skip to content

A study to compare between two combination of drugs dexmedetomidine and ropivacaine with budesonide and ropivacaine to check incidence of post operative sore throat after general anaesthesia.

A comparative study of efficacy of intratracheal dexmedetomidine and ropivacaine with intratracheal budesonide and ropivacaine in incidence and severity of post operative sore throat after general anaesthesia.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048256
Enrollment
130
Registered
2022-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine, ropivacaine: Will be used in combination of two groups, group 1 is dexmedetomidine(1mcg/kg) and ropivacaine(0.75% 35mg in 5ml) with group 2 Budesonide(200mcg) and ropi

Sponsors

Harsh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient of ASA 1 and ASA2 physical status 2. Patient between 18-65 years of age. 3. Patient with Mallampati class I-II. 4. Patient posted for major surgeries under General anaesthesia. 5. Patient wiling to participate.

Exclusion criteria

Exclusion criteria: 1. Patient refusal to participate. 2. Patient with ASA physical status III or above. 3. Patient aged less than 18 years and more than 65 years. 4. Patient with suspected difficult airway and Mallampati grade III or above. 5. Patient with pregnancy, morbid obesity and history of sore throat. 6. Patient transferred to ICU intubated after operation under general anaesthesia.

Design outcomes

Primary

MeasureTime frame
Post operative sore throat, pain on deglutition, hoarseness and coughTimepoint: Zero Hour(Just after Extubation, 2,4,6,12,24 hrs post extubation

Secondary

MeasureTime frame
Intraoperative hemodynamics changes in heart rate, blood pressure, MAP, oxygen saturationTimepoint: Before giving drug, before intubation, after intubation, after 15 min of surgery, after 30 minute of surgery, after Extubation

Countries

India

Contacts

Public ContactHarsh

Indira Gandhi Institute of Medical Scienecs

drbibha98aditi@gmail.com8252410069

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026