Comparsion between intravenous dexmedetomidine and tramadol for treatment of shivering after spinal anaesthesia

Comparative evaluation of intravenous dexmedetomidine and tramadol for treatment of shivering after spinal anaesthesia

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/12/048249

Enrollment

100

Registered

2022-12-19

Start date

Unknown

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R258- Other abnormal involuntary movements

Interventions

Control Intervention1: DEXMEDETOMIDINE: INTRAVENOUS,1mcg/kg given after onset of shivering.TOTAL DURATION OF OBSERVATION-1HR 30MIN Control Intervention2: TRAMADOL: INTRAVENOUS,1mg/kg given after onset

Eligibility

Inclusion criteria

Inclusion criteria: ASA GRADE 1&2 UNDERGOING LOWER ABDOMINAL,LOWER LIMB SURGERIES UNDER SPINAL ANESTHESIA

Exclusion criteria

Exclusion criteria: KNOWN HYPERSNSITIVITY TO DEXMEDETOMIDINE OR TRAMADOL CARDIO-PULMONARY,RENAL OR HEPATIC DISEASE HYPERTHYROIDISM PSYCHIATRIC DISORDER URINARY TRACT INFECTION SEVERE DIABETES OR AUTONOMIC NEUROPATHIES KNOWN HISTORY OF SUBSTANCEOR ALCOHOL ABUSE PATIENT RECEIVING ANY PRE-MEDICATION

Design outcomes

Primary

Measure	Time frame
TO COMPARE EFFICACY OF INTRAVENOUS DEXMEDETOMIDINE AND TRAMADOL FOR TREATMENT OF SHIVERING AFTER SPINAL ANESTHESIA ON THE BASIS OF TIME FOR CESSATION OF SHIVERING,RECURRENCE AND RESPONSE RATETimepoint: VITALS RECORDED AT INTERVAL OF EVERY 5MINUTES FOR FIRST 30MINUTE AND EVERY 15 MINUTES TILL 1HR 30MIN	—

Secondary

Measure	Time frame
COMPARISION OF ADVERSE EFFECTS FOLLOING ADMINISTRATION OF INTRAVENOUS DEXMEDETOMIDINE VERSUS TRAMADOL LIKE NAUSEA,VOMITING HYPOTENSION BRADYCARDIA SEDATIONTimepoint: 15 MINUTE,30 MINUTE,45 MINUTE,1 HOUR,1HR 15MIN,1HR 30 MIN	—

Countries

India

Contacts

Public ContactDR DEBJANI SETH

VEER SURENDRA SAI INSTITUTE OF MEDICAL SCIENCES AND RESEARCH,BURLA

drbimalpanda@gmail.com9437175425

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026