Skip to content

COMPARING THE EFFECTS OF TWO LOCAL ANAESTHESIA DRUGS FOR SPINAL ANESTHESIA

COMPARING THE EFFECT OF INTRATHECAL DEXMEDETOMIDINE AS AN ADJUVANT TO HYPERBARIC BUPIVACAINE AND HYPERBARIC ROPIVACAINE IN PATIENTS UNDERGOING LOWER LIMB ORTHOPEDIC SURGERIES

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048169
Enrollment
100
Registered
2022-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: S828- Other fractures of lower leg

Interventions

Intervention1: Sub-arachanoid block given with Hyperbaric Ropivacaine and Dexmedetomidine: 2.8ml of 0.75% Hyperbaric Ropivacaine + 0.1ml of 50mcg/ml Dexmedetomidine administered and the study paramete

Sponsors

M S RAMAIAH MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Elective lower limb Orthopedic surgeries. American Society of Anesthesiologists Physical Status 1 and 2.

Exclusion criteria

Exclusion criteria: Patients refusal to participate in the study. Contraindications to Spinal Anaesthesia. Pregnant women and lactating mothers. Patient allergic to Opiods and Local Anaesthetic drugs. Patient height <150cms.

Design outcomes

Primary

MeasureTime frame
To compare the effect on onset and duration of sensory block and onset and duration of motor block.Timepoint: The block will be assessed at 1 minute interval for the first 10 minutes, every 5 minutes in the first hour, every 10 minutes till the regression of block.

Secondary

MeasureTime frame
To compare the effect on hemodynamic changes in both the groups like hypotension, bradycardia and side effects such as nausea, vomiting, pruritius and shivering.Timepoint: Hemodynamic parameters measured at every 2 minute intervals for the first 10 minutes followed by 5 minute intervals for the next 20 minutes and at 10 minute intervals till the end of the surgery.

Countries

India

Contacts

Public ContactGEETHA C R

M S RAMAIAH MEDICAL COLLEGE

jageedha@yahoo.com9900482828

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026