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TO Observe the effectiveness of prophylactic phenylephrine infusion versus therapeutic phenylephrine bolus on maternal hemodynamics and neonatal outcome during elective cesarean section.

Evaluate the effectiveness of prophylactic phenylephrine infusion versus therapeutic phenylephrine bolus on maternal hemodynamics and neonatal outcome during elective cesarean section: A Observational study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048156
Enrollment
60
Registered
2022-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Prophylactic phenylephrine 0.5mcg/kg/min in group A started immediately after spinal anaesthesia,continued till completion of surgery. Therapeutic phenylephrine 50mcg bolus given i

Sponsors

Swai mansingh medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Healthy parturient(uncomplicated pregnancy without known foetal abnormalities) 2.age group 24-30year 3.Body wieght 40-80kg 4.Gestational age >36week

Exclusion criteria

Exclusion criteria: 1.patient younger than 18 year of age 2. preeclamptic patient 3. history of blood coagulopathies 4. patient allergic to drug used for study 5.uncooperative patients 6.patient with heart failure and mother with bradycardia.

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of prophylactic phenylephrine infusion and therapeutic bolus on mean maternal heart rate , mean Systolic,mean diastolic, mean arterial pressure during cesarean section under spinal anesthesia. Effect of prophylactic phenylephrine infusion and therapeutic bolus on incidence APGAR score. Timepoint: To evaluate the effect of prophylactic phenylephrine infusion and therapeutic bolus on maternal HR, SBP,DBP,MAP at baseline ,1min,2min .........till 10min. Effect of prophylactic phenylephrine infusion and therapeutic bolus on APGAR score at 1min and 5min—

Secondary

MeasureTime frame
1.propotion of cases with side effects . 2.percentage of neonates developing acidosis .Timepoint: 1. the number of patient developing complications from 0mim to 45min of spinal anaesthesia. 2.Percentage of neonates developing acidosis—

Countries

India

Contacts

Public ContactDR Shailaja

Swai mansingh medical college jaipur rajasthan

chatterjee.chandrashekhar@gmail.com9828088092

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026