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GUM THICKNESS MODIFICATION TRIAL

Regenerative phenotypic modification therapy: A non-randomized prospective pilot clinical trial (PMT TRIAL) - REGPHEN

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048131
Enrollment
10
Registered
2022-12-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K069- Disorder of gingiva and edentulousalveolar ridge, unspecified Health Condition 2: R69- Illness, unspecified Health Condition 3: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention1: FLEXIBLE BONE GRAFT WITH ENAMEL MATRIX DERIVATIVES: The surgical phase will include lateral access tunnel technique under local anesthesia using bilateral access one tooth adjacent to s

Sponsors

MINISTRY OF DEFENCE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (aa) Patients exhibiting thin periodontal osseous / soft tissue phenotype in 2 adjacent teeth on CBCT (Cone Beam Computed Tomography) / probe visibility method respectively. (ab) Full mouth bleeding scores less than 20%. (ac) Full mouth plaque scores less than 20%. (ad) ASA-I physical status (American Society of Anesthesiologists).

Exclusion criteria

Exclusion criteria: (aa) Patients who underwent any form of soft tissue / hard tissue grafting procedure at the site of interest. (ab) Current Smokers / Past Smokers within 1 year. (ac) Current Pregnant / Planned Pregnancy / Lactating women. (ad) Patient age group less than 18 or above 60 years.

Design outcomes

Primary

MeasureTime frame
Changes in Periodontal PhenotypeTimepoint: Baseline, 3 months, 6 months, 9 months 12 months, 15 months, 18 months and 24 months.

Secondary

MeasureTime frame
Incidence of gingival recession Thickness of gingiva Thickness of labial alveolar bone Width of keratinised gingivaTimepoint: Baseline, 12 months, 24 months

Countries

India

Contacts

Public ContactSARAVANAN SP

ARMY DENTAL CORPS

drsaravanan.sp@gmail.com9637110906

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026