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Opioid free anaesthesia

Evaluation of immediate quality of recovery with opioid free anaesthesia in patients undergoing gynaecological cancer surgeries- a randomised controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048126
Enrollment
80
Registered
2022-12-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C579- Malignant neoplasm of female genital organ, unspecified

Interventions

Intervention1: Opioid Free Anaesthesia(OFA): Patients in the group OFA will receive opioid free anaesthesia . These patients will receive dexmedetomidine infusion at 1mcg/kg over 10 minutes before ind

Sponsors

University College of Medical sciences and GTB Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consenting ASA grade I-II patients,aged 20-65 years, undergoing exploratory laparotomy for gynaecological cancer surgeries.

Exclusion criteria

Exclusion criteria: Patients with history of any etiology , postoperative nausea and vomiting,prior allergy to local anaesthetics or coagulopathies, patients receiving opioids and patients having inability to comprehend questionnaires

Design outcomes

Primary

MeasureTime frame
Quality of recovery QoR 40 score at 12th hr day 1 & day 3Timepoint: Quality of recovery QoR 40 score at 12th hr day 1 & day 3

Secondary

MeasureTime frame
To determine the pain intensity in the immediate postoperative period till day 3 To determine the rescue analgesic consumption in first 24 hrs To determine PONV scores in the immediate postoperative period in first 24 hrs To assess the neuropathic component of pain via DN-4 questionnaire.Timepoint: To determine the pain intensity in the immediate postoperative period till day 3 To determine the rescue analgesic consumption in first 24 hrs To determine PONV scores in the immediate postoperative period in first 24 hrs To assess the neuropathic component of pain via DN-4 questionnaire.

Countries

India

Contacts

Public ContactDr Geetanjali T Chilkoti

UCMS and GTB hospital

geetanjalidr@yahoo.in9711210772

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026