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Comparing the timing of dialysis before transplant in terms of strong ion difference

Effect of pre-transplant dialysis at 36 hours versus 16 hours on strong ion difference: non inferiority randomized clinical trial in renal transplant recipients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048116
Enrollment
60
Registered
2022-12-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Timing of dialysis: More than 36 hours interval between dialysis and renal transplant surgery Control Intervention1: Timing of dialysis: Less than 16 hours interval between dialysis and

Sponsors

PGIMER Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients presenting to PGIMER renal transplant between age 18-70 years. 2. Patients on alternate day dialysis regime 3. Patients receiving either of the live or cadaveric kidney

Exclusion criteria

Exclusion criteria: 1. Liver diseases 2. Hemodynamically unstable patients 3. Dilated Cardiomyopathy 4. Patients developing significant acid-base disturbance after intra-operative reperfusion, requiring Sodium Bicarbonate. 5. Patients on daily dialysis regime

Design outcomes

Primary

MeasureTime frame
Strong Ion DifferenceTimepoint: At induction and first post-operative hour—

Secondary

MeasureTime frame
Acidosis (difference in pH, bicarbonate, Base Excess)Timepoint: Pre-transplant and first post operative hour;Echocardiographic parameters (cardiac output, cardiac index, LVOT diameter, VTI, E/A, E/eâ?? and TAPSE)Timepoint: Pre-transplant;Global lung ultrasound scoreTimepoint: At induction and in the first postoperative hour;Incidence of delayed graft functionTimepoint: Postoperatively;Intraoperative fluid requirementTimepoint: Intraoperative;IVC diameter and IVC collapsibility index (IVCCI)Timepoint: At induction and in the first postoperative hour—

Countries

India

Contacts

Public ContactSubodh Zagade

PGIMER Chandigarh

kamal.kajal@gmail.com9560412726

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026