Comparison between two modes of ventilation in preterms who failed CPAP

Non Invasive Positive Pressure Ventilation(NIPPV) versus Conventional Mechanical Ventilation(CMV) in CPAP failed preterm babies â?? a non-inferiority study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/12/048106

Enrollment

Registered

2022-12-14

Start date

Unknown

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P229- Respiratory distress of newborn, unspecified

Interventions

Intervention1: Non invasive Positive Pressure ventilation: Babies who have failed CPAP will be put on NIPPV mode Duration till extubation to CPAP will be recorded Control Intervention1: Conventional M

Eligibility

Inclusion criteria

Inclusion criteria: • Babies who are • Respiratory distress requiring CPAP support for at least 2 hours • SOPI >1.6

Exclusion criteria

Exclusion criteria: • Babies having Major congenital anomalies • Congenital heart Disease excluding small ASD/VSD • Baby requiring major surgeries

Design outcomes

Primary

Measure	Time frame
Difference in variables like failure of intervention, mortality, duration of stay, complications between the two groupsTimepoint: Hours of Positive pressure ventilation	—

Secondary

Measure	Time frame
â?¢ Necrotising enterocolitis â?¢ Sepsis â?¢ Pneumothorax â?¢ IVH â?¢ BPD â?¢ Death Timepoint: Death or discharge	—

Countries

India

Contacts

Public ContactDR SRINIVASA MURTHY D

JSS Academy of Higher Education and Research

drdsrinivasa@gmail.com08212335555

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026