Health Condition 1: N201- Calculus of ureter
Conditions
Interventions
Intervention1: Deflazacort: Deflazacort tablet (12 mg once daily for 10 days) plus Tamsulosin tablet 0.4 mg once daily for 28 days, ORALLY
Control Intervention1: Tamsulosin: Tamsulosin tablet 0.4 mg o
Sponsors
Dr Arka Banerjee
Eligibility
Inclusion criteria
Inclusion criteria: 1.Subjects attending surgery OPD with diagnosis of ureteric stone 2.Subjects of either sex aged between 18-60 years. 3.Female subjects of reproductive age group willing to practice a medically accepted means of contraception. 4.Subjects willing to provide written informed consent for this study.
Exclusion criteria
Exclusion criteria: 1.Ureteric stone measured > 10 millimeter in size 2.Patients with fever, high-grade hydronephrosis, acute kidney failure, UTI 3.Patients with history of urinary surgery or endoscopic treatment 4.Patients with Pregnancy, breastfeeding, Diabetes, Chronic kidney disease, peptic ulcer, hypotension, liver failure, Benign Prostate Hyperplasia, Hypertension, 5.Concomitant treatment with alpha-blocker drugs, betablockers, calcium channel blockers or nitrates 6.Declared hypersensitivity to Tamsulosin or corticosteroids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of low dose Deflazacort and Tamsulosin versus Tamsulosin alone in ureteric stone expulsionTimepoint: . Rate of stone expulsion of stone from ureter in 4 week follow up time | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess symptomatic improvement with low dose Deflazacort when added to Tamsulosin To Find out safety and tolerability of study drugs Timepoint: at day 14 after starting treatment and at day 28 after starting treatment | — |
Countries
India
Contacts
Public ContactHindol Mondal
Malda Medical College
Outcome results
None listed