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A clinical trial to study effect of bio-glue in patients for the closure of wounds following oral surgery.

Efficacy of cyanoacrylate tissue adhesive for intraoral wound closure: a prospective study.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/048035
Enrollment
50
Registered
2022-12-12
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: K069- Disorder of gingiva and edentulousalveolar ridge, unspecified Health Condition 3: K011- Impacted teeth Health Condition 4: K136- Irritative hyperplasia of oral mucosa Health Condition 5: K116- Mucocele of salivary gland Health Condition 6: K041- Necrosis of pulp

Interventions

Intervention1: n-butyl and 2-octyl cyanoacrylates(PeriAcryl 90 High Viscosity, GluStitch): Commercially available synthetic tissue adhesive applied using a pipette. Duration of intervention : 3 minute

Sponsors

Dr Kanishk Srivastava
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient with the age 18 years and above will be selected for the study. 2.Minor oral surgical procedures were closure of intra oral surgical incisions are required 3.Procedures like, multiple extractions, canine exposure, transalveolar extractions, surgical extraction of impacted third molars and canine, alveoloplasty, biopsy, and excision of mucocele are included in the study. 4.Clean incisions which can be approximated without tension are included. 5.Patient who agreed to follow the study protocol.

Exclusion criteria

Exclusion criteria: Patients will not be considered for the study with the following criteria: 1.Immunocompromised patients. 2.Uncontrolled diabetes 3.Bleeding disorders 4.Uncooperative patients 5.Neurological disorders

Design outcomes

Primary

MeasureTime frame
Improved and early wound healing of test siteTimepoint: 1 week

Secondary

MeasureTime frame
Efficacy of tissue adhesive for early wound healing of the surgical site, healing will be much better and patients compliance will be more towards the product under investigation.Timepoint: 3rd and 7th day post op.

Countries

India

Contacts

Public ContactDr Senthil K Kumar

Dr.M.G.R. Educational and Research Institute

senthilomfs@gmail.com9884634754

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026