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Study on nutrition and age-related muscle loss in an Indian population

Characterizing plasma metabolites/ lipids and gut microbiome profile as biomarkers of susceptibility to sarcopenia in the elderly

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/12/048031
Enrollment
60
Registered
2022-12-12
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M625- Muscle wasting and atrophy, not elsewhere classified

Interventions

None listed

Sponsors

Institute for Stem Cell Science and Regenerative Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Stable health and ability to be independent/ autonomous 2. with grip strength suggesting sarcopenia and MRI showing sarcopenia 3.with long bone fracture requiring immobilisation

Exclusion criteria

Exclusion criteria: 1. Congenital muscludytrophies 2. Chronic cardiopulmonary insufficiency 3. Severe liver damage (cut-off of transaminase levels) requiring limited protein intake 4. Presence of malignant neoplastic disease (which may cause Cachexia)

Design outcomes

Primary

MeasureTime frame
Quantifying plasma nutrients, IGF-1, IL6, TroponinT, metabolites and lipids from control, sarcopenic and fractured subjectsTimepoint: 24hr—

Secondary

MeasureTime frame
Measuring changes in intestinal microbiota between control, sarcopenic and fractured patients using DNA sequencing of the metagenome.Timepoint: 24hr—

Countries

India

Contacts

Public ContactDr Aravind Ramnathan

Institute for Stem Cell Science and Regenerative Medicine

arvind@instem.res.in9482775648

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026