Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Oral Melatonin: 3mg two tablet given (6mg) 2 hours prior to surgery
for Attenuation of hemodynamic response during laryngoscopy ie heart rate , systolic and diastolic blood pressure an
Sponsors
ROHILKHAND MEDICAL COLLEGE AND HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA Grade 1 or 2 2.Posted for 2 hour long elective surgeries under General Anaesthesia
Exclusion criteria
Exclusion criteria: 1.Patient refusal for procedure 2.Patient with history of cardiac, pulmonary or renal disease 3.Taking sedatives, hypnotics or anti-hypertensive medication 4.Any known allergy to Local anaesthetic 5.BMI >3O kg per meter square 6.Pregnant or breastfeeding females
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Heart rate , systolic blood pressure , diastolic blood pressure and Mean arterial pressure at different interval (before , during and after induction)Timepoint: 1 min , 3 mins , 5mins and 10 mins | — |
Secondary
| Measure | Time frame |
|---|---|
| sedation by ramsay sedation score - preoperative prior to administration of study drug , before induction , after extubation, postoperatively at different interval. Pain by numerical rating scale after extubation postoperativelyTimepoint: 60 mins and 120 mins | — |
Countries
India
Contacts
Public ContactNeeharika Arora
ROHILKHAND MEDICALCOLLEGE AND HOSPITAL
Outcome results
None listed