A Comparative trial between outcomes from Laparoscopic Surgical Management vs Non Surgical Management in Acute Appendicitis

Laparoscopic Appendectomy vs Non-Operative Management In Acute Appendicitis. A Randomized Control Trial. - LANO Trial

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/12/047976

Enrollment

152

Registered

2022-12-08

Start date

Unknown

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K352- Acute appendicitis with generalized peritonitis Health Condition 2: K353- Acute appendicitis with localizedperitonitis Health Condition 3: O- Medical and Surgical Health Condition 4: K358- Other and unspecified acute appendicitis

Interventions

Intervention1: LAPAROSCOPIC APPENDECTOMY: STANDARD LAPAROSCOPIC APPENDECTOMY + ANTIBIOTIC MANAGMENT Antibiotics being used intravenously 1st line â?? Cefoperazone + Sulbactam (2 grams q12hr) and Metr

Eligibility

Inclusion criteria

Inclusion criteria: Patients will be included from the age group of 18-65 years old clinically and radiologically diagnosed with acute uncomplicated appendicitis. Patients consenting to participate in the study after being explained about the procedure and its associated complications and possible outcomes.

Exclusion criteria

Exclusion criteria: Pregnant women Patients with complicated appendicitis. Patients deemed unfit for Anesthesia. Patients with previous history of acute appendicitis or its sequelae. Previously attempted laparoscopic/open appendectomy.

Design outcomes

Primary

Measure	Time frame
Complete resolution of symptoms Post intervention procedure with no recurrence of symptoms in the follow up period.Timepoint: At baseline 1 week post intervention 1 month post intervention 3 months post intervention	—

Secondary

Measure	Time frame
Operative time, Duration of Hospital stay, Need for readmission or interventionTimepoint: Recurrence of symptoms at any point from time of diagnosis till 3 months thereafter	—

Countries

India

Contacts

Public ContactSHARAN KUMAR S

ALL INDIA INSTITUTE OF MEDICAL SCIENCES

rajinderparshad@aiims.edu9868397715

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026