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Repetitive Transcranial Magnetic Stimulation as adjunct to Speech therapy in Post Stroke Aphasia

A Randomised Controlled Trial comparing the efficacy of NIBS (low frequency inhibitory rTMS) in addition to standard of care vs standard of care alone in post stroke aphasia.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/047931
Enrollment
22
Registered
2022-12-07
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G938- Other specified disorders of brain

Interventions

Intervention1: low frequency rTMS to Right Inferior Frontal Gyrus: All the patients will be given standard of care speech therapy. Patients will then be randomised into the two arms: Arm A will inclu

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i) Age 18-70 years ii) Left MCA territory ( ischaemic or haemorrhagic ) iii) 2 weeks â?? 6 month following index event iv) Right handed individuals ( assessed by Edinburgh Handedness Inventory )

Exclusion criteria

Exclusion criteria: Exclusion Criteria: i. A coexistent diagnosis of epilepsy / Seizure within last 1 year / On anti-epileptic drugs ii. Patients with pre-morbid cognitive decline/ Patients with intellectual disability iii. Patients with acute psychosis iv. Hemodynamically unstable/ Intubated patients v. Any co-existing acute lung/cardiac/renal/liver disease vi. Patients having contraindication to MRI vii. Patients not giving consent

Design outcomes

Primary

MeasureTime frame
Change in Global BDAE scoreTimepoint: 2 - baseline and 3 months post intervention

Secondary

MeasureTime frame
change in SF-36 quality of life change in Hamilton Depression ScaleTimepoint: 2- baseline and at 3 months post intervention

Countries

India

Contacts

Public ContactSampurna Chowdhury

AIIMS, New Delhi

sampurna21@icloud.com919674218643

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026