Health Condition 1: S34- Injury of lumbar and sacral spinalcord and nerves at abdomen, lower back and pelvis level Health Condition 2: S14- Injury of nerves and spinal cord at neck level Health Condition 3: S24- Injury of nerves and spinal cord at thorax level
Conditions
Interventions
Control Intervention1: calcium: To observe the effect of single dose of calcium 500mg by oral route in spinal cord injury patients after two hours of administration
Control Intervention2: Calcium: To
Sponsors
Sawai Man Singh Medical College Jaipur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients willingly giving an informed written consent to participate in study 2. Age group 18-65 year 3. Traumatic spinal cord injury with supra sacral lesion 4. Patient with compromise lower urinary tract functions
Exclusion criteria
Exclusion criteria: 1. Patient with diagnosed renal, liver, Cardiovascular, diabetes mellitus or any other medical illness where urodynamic study canâ??t be performed 2. Patient with history of allergy to tadalafil 3. Patient with urinary tract infection, diagnosed at the time of screening by urine analysis and urine culture 4. Any anatomical abnormalities where urodynamic study canâ??t be performed. 5. Patent with history of major pelvic surgery e.g. prostatectomy, augmentation cystoplasty or colectomy 6. Traumatic spinal cord injury patients with spinal shock. 7. Traumatic spinal cord injury patients LMN type bladder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Maximum detrusor filling pressure 2. Maximum bladder capacity 3. Bladder compliance 4. Change in maximum detrusor pressure at the time of leaking/voiding. 5. Observe the side effect/s of tadalafil in study group.Timepoint: BASELINE | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the side effect profile of tadalafil in study group patients.Timepoint: at follow-up assessment | — |
Countries
India
Contacts
Public ContactDR OMPRAKASH
SAWAI MANSINGH MEDICAL COLLEGE
Outcome results
None listed