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Effect of intravenous calcium in the prevention of uterine relaxation in women undergoing emergency cesarean section under spinal anaesthesia.

Effect of prophylactic intravenous calcium in the prevention of uterine atony among women undergoing emergency cesarean under spinal anaesthesia:a randomized clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/047912
Enrollment
367
Registered
2022-12-06
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O721- Other immediate postpartum hemorrhage

Interventions

Intervention1: Calcium gluconate: 1 gram of calcium gluconate diluted with NS to a total volume of 50 ml delivered via infusion pump at rate of 300 ml/hr over 10 mins after clamping of cord via intra

Sponsors

Jawaharlal Institute of Postgraduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: emergency cesarean delivery under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1.Patients with hypercalcemia. 2.Patients with preeclampsia on magnesium sulphate or calcium channel blockers 3.Patients with obstetric conditions like placenta previa and abruption. 4. Renal dysfunction with serum Creatinine > 1.0 mg/dl. 5. Patients with abnormal cardiac function or history of arrhythmia.

Design outcomes

Primary

MeasureTime frame
To compare the effect of intravenous calcium administration on uterine tone which will be asssessed by the obstetrician based on numerical scale score (0-completely atonic 10-fully contracted)among women undergoing cesarean delivery under spinal anaesthesia. Timepoint: 0,5,10,15,20 mins ater clamping of cord

Secondary

MeasureTime frame
To compare the intraoperative blood loss, need for additional uterotonic requirements(methylergometrine, prostaglandin F2a, Prostagalndin E1 etc),mechanical surgical interventions (uterine balloon, B-lynch sutures etc), total fluid, vasopressors,total oxytocin bolus, transfusion requirements between the two groups. Timepoint: At the end of surgery

Countries

India

Contacts

Public ContactDr Abirami T L

Jawaharlal Institute of Postgraduate Medical Education and Research

priyaab8@gmail.com8903477132

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 5, 2026