Health Condition 1: G891- Acute pain, not elsewhere classified Health Condition 2: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
Conditions
Interventions
Intervention1: Ketoprofen transdermal patch: 20mg single transdermal patch is applied on the non hairy part of the back of the subject and pain is assessed over the first 24 hours postoperative perio
Sponsors
nil
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects willing to give written informed consent. 2. Adults above 18 years and below 65 years of age of either gender. 3. Subjects who are undergoing upper limb fracture fixation surgery.
Exclusion criteria
Exclusion criteria: 1. Subjects having history of heart block, bronchial asthma, bleeding disorders, on anticoagulants, active peptic ulcer disease, skin diseases, liver and kidney disorders and drug/alcohol abuse 2. Pregnant and Lactating mothers 3. Subjects with hypersensitivity to the study medications 4. Subjects with poly trauma. 5. Subjects operated under general anaesthesia. 6. Subjects with contraindications to regional block. 7. Subjects with history of peripheral neuropathy and pre-existing nerve damage in the operative arm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain assessment using Verbal Rating Scale and Numerical Rating ScaleTimepoint: 0hour, 4hour, 8hour, 12hour and 24hour postoperative period | — |
Secondary
| Measure | Time frame |
|---|---|
| Need for rescue analgesicTimepoint: Within the first 24hour postoperative period;Timing of rescue analgesic administrationTimepoint: From the time of surgery | — |
Countries
India
Contacts
Public ContactDr Chethan B
Department of Pharmacology, Kempegowda Institute of Medical Sciences, Bangalore
Outcome results
None listed