Health Condition 1: L400- Psoriasis vulgaris
Conditions
Interventions
Intervention1: Heartfulness meditation and standard treatment (Oral methotrexate): 1. Methotrexate standard weekly dose for psoriasis will be given. Dose ranging from 7.5mg/week to 25mg/week
2. Heartf
Sponsors
AIIMS Mangalagiri
Eligibility
Inclusion criteria
Inclusion criteria: • Consecutive consenting patients of both genders aged 18-60 years, attending dermatology OPD of AIIMS Mangalagiri diagnosed with moderate to severe psoriasis • Definition of moderate to severe psoriasis is (BSA > 10 or PASI >10) and DLQI > 10. Special clinical situations may change mild psoriasis to moderate to severe including involvement of visible areas or severe nail involvement.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women 2. Pre-existing psychiatric illness 3. Pre-existing illnesses like hepatic and renal disease, connective tissue diseases, and malignancies 4. Disease onset within the last 3 months 5. Patients who are practicing yoga/meditation regularly in the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time taken to achieve PASI 75 score.(75% reduction of disease severity from baseline)Timepoint: After 4 months of intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Effectiveness of the meditation on the changes in the serum levels of interleukin 6, and serum cortisol in patients with psoriasis 2. Effectiveness of the intervention on the changes in the stress scores and sleep scores.Timepoint: After 4 months of intervention | — |
Countries
India
Contacts
Public ContactPrabhakaran N
AIIMS Mangalagiri
Outcome results
None listed