Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: Etoricoxib: Tablet. Etoricoxib - 60 mg BD orally for one month.
Intervention2: Piroxicam: Tablet. Piroxicam - 20 mg BD orally for one month.
Control Intervention1: 1. Etoricoxib
2. Piro
Sponsors
PRINC BGHEAL
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with symptomatic osteoarthritis of age 35 to 65 years who fulfill the western Ontario and McMaster universities osteoarthritis index (WOMAC) 2. Criterion for the diagnosis of osteoarthritis will be enrolled. 3. Patients having symptomatic Osteoarthritis either as a new case or as an old case following discontinuation of treatment with NSAIDS or other analgesic medications with a washout period of one week 4. All these patients will be examined as per the baseline criteria will be included in the study if they fit this criterion.
Exclusion criteria
Exclusion criteria: 1. Smokers/ alcoholics 2. Pregnant & lactating women. 3. Patients on steroid therapy, history of chronic infections like TB, leprosy, recent trauma, surgery, mental retardation, minor. 4. Patients with liver diseases, kidney diseases, and cardiac problems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Pain, Stiffness, physical Function - measured with Western Ontario and McMaster Universities Arthritis Index (WOMAC). 2. Adverse effects: Total number of adverse effects (all), Gastrointestinal adverse effects (for example, nausea, vomiting), Neurological (nervous system) adverse effects (for example, headache, fatigue, dizziness).Timepoint: one month | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement - measured with a Patient Global Impression Scale of Improvement (PGI) as a quality indicator.Timepoint: one month | — |
Countries
India
Contacts
Public ContactPRINC BGHEAL
RAMA MEDICAL COLLEGE, HOSPITAL AND RESEARCH CENTRE
Outcome results
None listed